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Turner syndrome manifests itself differently in each female affected by the condition; therefore, no two individuals share the same features.
While most of the physical findings are harmless, significant medical problems can be associated with the syndrome.
This abnormality is a relatively rare congenital heart disease in the general population.
The prevalence of this abnormality also is low (around 2.9%) in Turner syndrome.
Turner syndrome is often associated with persistent hypertension, sometimes in childhood.
In the majority of Turner syndrome patients with hypertension, no specific cause is known.
Estimates of the prevalence of this malformation in patients with Turner syndrome range from 6.9 to 12.5%.
A coarctation of the aorta in a female is suggestive of Turner syndrome and suggests the need for further tests, such as a karyotype.
Two studies found a rate of cardiovascular malformations of 30% The higher rate in the group of pure 45, X monosomy is primarily due to a difference in the rate of aortic valve abnormalities and coarctation of the aorta, the two most common cardiovascular malformations.
The most commonly observed are congenital obstructive lesions of the left side of the heart, leading to reduced flow on this side of the heart.
It is usually isolated, but it may be seen in combination with other anomalies, particularly coarctation of the aorta.